Activated Ras signals differentiation and expansion of CD4+8+ thymocytes.

We describe a novel approach to assay the ability of particular gene products to signal transitions in lymphocyte differentiation in vivo. The method involves transfection of test expression constructs into RAG-1-deficient embryonic stem cells, which are subsequently assayed by the RAG-2-deficient b...

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Detalles Bibliográficos
Main Authors: Swat, W, Shinkai, Y, Cheng, H L, Davidson, L, Alt, F W
Formato: Artigo
Idioma:Inglês
Publicado: 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC39339/
https://ncbi.nlm.nih.gov/pubmed/8643464
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