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Hyaluronidase-Sensitive Nanoparticle Templates for Triggered Release of HIV/AIDS Microbicide In Vitro

This study was designed to test the hypothesis that a triggered release of a topical microbicide (tenofovir) from hyaluronic acid nanoparticles (HA-NPs) can be achieved under the influence of hyaluronidase (HAase) enzyme. A fractional factorial experimental design was used to examine the factors [mo...

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Detalhes bibliográficos
Main Authors: Agrahari, Vivek, Zhang, Chi, Zhang, Tao, Li, Wenjing, Gounev, Todor K., Oyler, Nathan A., Youan, Bi-Botti C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933588/
https://ncbi.nlm.nih.gov/pubmed/24343770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9546-7
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