Real-Time Analysis of Tenofovir Release Kinetics Using Quantitative Phosphorus ((31)P) Nuclear Magnetic Resonance Spectroscopy

The dialysis method is classically used for drug separation before analysis, but, does not provide direct and real-time drug quantification and has limitations affecting the dialysis rate. In this study, a phosphorus nuclear magnetic resonance ((31)P-qNMR) method is developed for the real-time quant...

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Vydáno v:J Pharm Sci
Hlavní autoři: Agrahari, Vivek, Meng, Jianing, Purohit, Sudhaunshu S., Oyler, Nathan A., Youan, Bi-Botti C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757512/
https://ncbi.nlm.nih.gov/pubmed/28414145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.03.043
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