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Direct and real-time quantification of tenofovir release from pH-sensitive microparticles into simulated biological fluids using (1)H-NMR

In vitro drug release evaluation is a very important step toward the quality control of nano- or micro-particular drug delivery systems. However, most quantitative techniques such as HPLC requires a dialysis membrane to separate the released free drug from these delivery systems, thus are not capabl...

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Hlavní autoři: Zhang, Chi, Zhang, Tao, Oyler, Nathan A., Youan, Bi-Botti C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003498/
https://ncbi.nlm.nih.gov/pubmed/24765652
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