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Engineering Tenofovir Loaded Chitosan Nanoparticles: To Maximize Microbicide Mucoadhesion
The objective of this study was to engineer a model anti-HIV microbicide (Tenofovir) loaded chitosan based nanoparticles (NPs). Box-Behnken design allowed to assess the influence of formulation variables on the size of NPs and drug encapsulation efficiency (EE%) that were analyzed by dynamic light s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375325/ https://ncbi.nlm.nih.gov/pubmed/21704704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2011.06.007 |
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