A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

Statins are widely prescribed for lowering plasma low-density lipoprotein (LDL) concentrations and cardiovascular disease risk(1), but there is considerable interindividual variation in treatment response(2,3) and increasing concern regarding the potential for adverse effects, including myopathy(4)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mangravite, Lara M., Engelhardt, Barbara E., Medina, Marisa W., Smith, Joshua D., Brown, Christopher D., Chasman, Daniel I., Mecham, Brigham H., Howie, Bryan, Shim, Heejung, Naidoo, Devesh, Feng, QiPing, Rieder, Mark J., Chen, Y-D I., Rotter, Jerome I., Ridker, Paul M., Hopewell, Jemma C., Parish, Sarah, Armitage, Jane, Collins, Rory, Wilke, Russell A., Nickerson, Deborah A., Stephens, Matthew, Krauss, Ronald M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933266/
https://ncbi.nlm.nih.gov/pubmed/23995691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12508
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia