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Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

BACKGROUND: Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three tria...

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Autors principals: Barber, Mathew J., Mangravite, Lara M., Hyde, Craig L., Chasman, Daniel I., Smith, Joshua D., McCarty, Catherine A., Li, Xiaohui, Wilke, Russell A., Rieder, Mark J., Williams, Paul T., Ridker, Paul M., Chatterjee, Aurobindo, Rotter, Jerome I., Nickerson, Deborah A., Stephens, Matthew, Krauss, Ronald M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842298/
https://ncbi.nlm.nih.gov/pubmed/20339536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009763
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