Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations

BACKGROUND: Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three tria...

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Detalhes bibliográficos
Main Authors: Barber, Mathew J., Mangravite, Lara M., Hyde, Craig L., Chasman, Daniel I., Smith, Joshua D., McCarty, Catherine A., Li, Xiaohui, Wilke, Russell A., Rieder, Mark J., Williams, Paul T., Ridker, Paul M., Chatterjee, Aurobindo, Rotter, Jerome I., Nickerson, Deborah A., Stephens, Matthew, Krauss, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842298/
https://ncbi.nlm.nih.gov/pubmed/20339536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009763
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