Characterization of Statin Dose-response within Electronic Medical Records

Efforts to define the genetic architecture underlying variable statin response have met with limited success possibly because previous studies were limited to effect based on one-single-dose. We leveraged electronic medical records (EMRs) to extract potency (ED(50)) and efficacy (E(max)) of statin d...

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Autori principali: Wei, Wei-Qi, Feng, Qiping, Jiang, Lan, Waitara, Magarya S., Iwuchukwu, Otito F., Roden, Dan M., Jiang, Min, Xu, Hua, Krauss, Ronald M., Rotter, Jerome I., Nickerson, Deborah A., Davis, Robert L., Berg, Richard L., Peissig, Peggy L., McCarty, Catherine A., Wilke, Russell A., Denny, Joshua C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944214/
https://ncbi.nlm.nih.gov/pubmed/24096969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.202
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