Characterization of Statin Dose-response within Electronic Medical Records

Efforts to define the genetic architecture underlying variable statin response have met with limited success possibly because previous studies were limited to effect based on one-single-dose. We leveraged electronic medical records (EMRs) to extract potency (ED(50)) and efficacy (E(max)) of statin d...

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Hlavní autoři: Wei, Wei-Qi, Feng, Qiping, Jiang, Lan, Waitara, Magarya S., Iwuchukwu, Otito F., Roden, Dan M., Jiang, Min, Xu, Hua, Krauss, Ronald M., Rotter, Jerome I., Nickerson, Deborah A., Davis, Robert L., Berg, Richard L., Peissig, Peggy L., McCarty, Catherine A., Wilke, Russell A., Denny, Joshua C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944214/
https://ncbi.nlm.nih.gov/pubmed/24096969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.202
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