Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α

One of the major metabolic changes associated with cellular transformation is enhanced nutrient utilization, which supports tumor progression by fueling both energy production and providing biosynthetic intermediates for growth. The liver kinase B1 (LKB1) is a serine/threonine kinase and tumor suppr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Faubert, Brandon, Vincent, Emma E., Griss, Takla, Samborska, Bozena, Izreig, Said, Svensson, Robert U., Mamer, Orval A., Avizonis, Daina, Shackelford, David B., Shaw, Reuben J., Jones, Russell G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932920/
https://ncbi.nlm.nih.gov/pubmed/24550282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312570111
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak