AMPK is a negative regulator of the Warburg Effect and suppresses tumor growth in vivo

AMPK is a metabolic sensor that helps maintain cellular energy homeostasis. Despite evidence linking AMPK with tumor suppressor functions, the role of AMPK in tumorigenesis and tumor metabolism is unknown. Here we show that AMPK negatively regulates aerobic glycolysis (the Warburg effect) in cancer...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Faubert, Brandon, Boily, Gino, Izreig, Said, Griss, Takla, Samborska, Bozena, Dong, Zhifeng, Dupuy, Fanny, Chambers, Christopher, Fuerth, Benjamin J., Viollet, Benoit, Mamer, Orval A., Avizonis, Daina, DeBerardinis, Ralph J., Siegel, Peter M., Jones, Russell G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545102/
https://ncbi.nlm.nih.gov/pubmed/23274086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.12.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados