LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

BACKGROUND: Germline and somatic mutations in STK11, the gene encoding the serine/threonine kinase LKB1, are strongly associated with tumorigenesis. While loss of LKB1 expression has been linked to breast cancer, the mechanistic role of LKB1 in regulating breast cancer development, metastasis, and t...

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Autori principali: Dupuy, Fanny, Griss, Takla, Blagih, Julianna, Bridon, Gäelle, Avizonis, Daina, Ling, Chen, Dong, Zhifeng, Siwak, Doris R, Annis, Matthew G, Mills, Gordon B, Muller, William J, Siegel, Peter M, Jones, Russell G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178213/
https://ncbi.nlm.nih.gov/pubmed/24280377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-18
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