Inhibition of prostaglandin endoperoxide synthetase by thiol analogues of prostaglandin.
A variety of thiol compounds inhibited the enzymatic bis-oxygenation of 8,11,14-eicosatrienoic acid to prostaglandin G1, as examined with a purified preparation of prostaglandin endoperoxide synthetase (prostaglandin synthase; 8,11,14-eicosatrienoate, hydrogen-donor:oxygen oxidoreductase; EC 1.14.99...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/402003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.1.144 |
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