The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein.
Aspirin (acetylsalicylic acid) inhibits platelet prostaglandin synthesis and the ADP- and collagen-induced platelet release reaction. The mechanism of the inhibitory effect is unknown but may involve protein acetylation, since aspirin acetylates a variety of substrates, including platelet protein. W...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1975
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1159076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108132 |
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