The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein.

Aspirin (acetylsalicylic acid) inhibits platelet prostaglandin synthesis and the ADP- and collagen-induced platelet release reaction. The mechanism of the inhibitory effect is unknown but may involve protein acetylation, since aspirin acetylates a variety of substrates, including platelet protein. W...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Roth, G J, Majerus, P W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1975
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1159076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108132
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