Inhibition of prostaglandin endoperoxide synthetase by thiol analogues of prostaglandin.

A variety of thiol compounds inhibited the enzymatic bis-oxygenation of 8,11,14-eicosatrienoic acid to prostaglandin G1, as examined with a purified preparation of prostaglandin endoperoxide synthetase (prostaglandin synthase; 8,11,14-eicosatrienoate, hydrogen-donor:oxygen oxidoreductase; EC 1.14.99...

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Detalles Bibliográficos
Main Authors: Ohki, S, Ogino, N, Yamamoto, S, Hayaishi, O, Yamamoto, H
Formato: Artigo
Idioma:Inglês
Publicado: 1977
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC393214/
https://ncbi.nlm.nih.gov/pubmed/402003
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