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Insights into the structure of class B GPCRs

The secretin-like (class B) family of G protein-coupled receptors (GPCRs) are key players in hormonal homeostasis and are interesting drug targets for the treatment of several metabolic disorders (type 2 diabetes, osteoporosis, obesity) and nervous system diseases (migraine, anxiety, depression). Th...

詳細記述

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書誌詳細
主要な著者: Hollenstein, Kaspar, de Graaf, Chris, Bortolato, Andrea, Wang, Ming-Wei, Marshall, Fiona H., Stevens, Raymond C.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931419/
https://ncbi.nlm.nih.gov/pubmed/24359917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2013.11.001
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