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PEGylated drugs in rheumatology—why develop them and do they work?

Lack of efficacy and drug-related adverse effects are important reasons for the discontinuation of treatment in patients with rheumatic diseases. The development of new biologic therapies seeks to address these problems by specifically targeting the pathogenic mechanisms of disease. Most current bio...

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Détails bibliographiques
Auteurs principaux: McDonnell, Thomas, Ioannou, Yiannis, Rahman, Anisur
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930883/
https://ncbi.nlm.nih.gov/pubmed/23962623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket278
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