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PEGylated drugs in rheumatology—why develop them and do they work?

Lack of efficacy and drug-related adverse effects are important reasons for the discontinuation of treatment in patients with rheumatic diseases. The development of new biologic therapies seeks to address these problems by specifically targeting the pathogenic mechanisms of disease. Most current bio...

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Detalhes bibliográficos
Main Authors: McDonnell, Thomas, Ioannou, Yiannis, Rahman, Anisur
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930883/
https://ncbi.nlm.nih.gov/pubmed/23962623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket278
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