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Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow

Differential expression of the closely linked γ, β(A) (or β(B)), and β(C) globin genes in sheep results in the production of fetal hemoglobin (Hb F, α(2)γ(2)) during gestation and the adult hemoglobins (Hb A, α(2)β(2)(A), and Hb B, α(2)β(2)(B)) after birth. Erythropoietic stress in certain animals l...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Young, Neal S., Benz, Edward J., Kantor, Judith A., Kretschmer, Peter, Nienhuis, Arthur W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1978
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5884
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