Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow

Differential expression of the closely linked γ, β(A) (or β(B)), and β(C) globin genes in sheep results in the production of fetal hemoglobin (Hb F, α(2)γ(2)) during gestation and the adult hemoglobins (Hb A, α(2)β(2)(A), and Hb B, α(2)β(2)(B)) after birth. Erythropoietic stress in certain animals l...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Young, Neal S., Benz, Edward J., Kantor, Judith A., Kretschmer, Peter, Nienhuis, Arthur W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1978
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5884
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