Hemoglobin switching in sheep: Only the γ gene is in the active conformation in fetal liver but all the β and γ genes are in the active conformation in bone marrow

Differential expression of the closely linked γ, β(A) (or β(B)), and β(C) globin genes in sheep results in the production of fetal hemoglobin (Hb F, α(2)γ(2)) during gestation and the adult hemoglobins (Hb A, α(2)β(2)(A), and Hb B, α(2)β(2)(B)) after birth. Erythropoietic stress in certain animals l...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Young, Neal S., Benz, Edward J., Kantor, Judith A., Kretschmer, Peter, Nienhuis, Arthur W.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1978
Pynciau:	Biological Sciences: Biochemistry
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5884
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