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Structure of the oxygen adduct intermediate in the bacterial luciferase reaction: (13)C nuclear magnetic resonance determination

By using FMN enriched in (13)C (90%) at position C-4a, we have conclusively shown that the reaction of molecular oxygen with bacterial luciferase-bound FMNH(2) forms an adduct at the 4a position. Consistent with this are (13)C NMR studies of FMN and other flavin compounds which show that this carbon...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ghisla, Sandro, Hastings, J. Woodland, Favaudon, Vincent, Lhoste, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1978
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5860
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