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Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors

The enhancement of DNA synthesis by epidermal growth factor (EGF) in cultured human fibroblasts is demonstrable 24 hr after incubation of the cells at 37°C with very low concentrations (0.83 nM) of the hormone for very short periods (30 min) followed by thorough washing of the cells to remove the fr...

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Bibliografiska uppgifter
Huvudupphovsmän: Shechter, Yoram, Hernaez, Lydia, Cuatrecasas, Pedro
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1978
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC393060/
https://ncbi.nlm.nih.gov/pubmed/215996
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