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Identification of the Cardiac Beta-Adrenergic Receptor Protein: Solubilization and Purification by Affinity Chromatography

A protein that binds catecholamines with a specificity parallel to that of their in vivo effects on cardiac contractility (isoproterenol > epinephrine or norepinephrine > dopamine > dihydroxyphenylalanine) was solubilized from a microsomal fraction of canine ventricular myocardium. The bind...

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Bibliografiske detaljer
Main Authors: Lefkowitz, Robert J., Haber, Edgar, O'Hara, Donald
Format: Artigo
Sprog:Inglês
Udgivet: 1972
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC389654/
https://ncbi.nlm.nih.gov/pubmed/4507606
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