Identification of the Cardiac Beta-Adrenergic Receptor Protein: Solubilization and Purification by Affinity Chromatography

A protein that binds catecholamines with a specificity parallel to that of their in vivo effects on cardiac contractility (isoproterenol > epinephrine or norepinephrine > dopamine > dihydroxyphenylalanine) was solubilized from a microsomal fraction of canine ventricular myocardium. The binding prote...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lefkowitz, Robert J., Haber, Edgar, O'Hara, Donald
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1972
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4507606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.10.2828
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