Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors
The enhancement of DNA synthesis by epidermal growth factor (EGF) in cultured human fibroblasts is demonstrable 24 hr after incubation of the cells at 37°C with very low concentrations (0.83 nM) of the hormone for very short periods (30 min) followed by thorough washing of the cells to remove the fr...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1978
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/215996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5788 |
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