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Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors

The enhancement of DNA synthesis by epidermal growth factor (EGF) in cultured human fibroblasts is demonstrable 24 hr after incubation of the cells at 37°C with very low concentrations (0.83 nM) of the hormone for very short periods (30 min) followed by thorough washing of the cells to remove the fr...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Shechter, Yoram, Hernaez, Lydia, Cuatrecasas, Pedro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1978
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/215996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.5788
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