Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice

Apolipoprotein E-null mice on a DBA/2J genetic background (DBA-apoE) are highly susceptible to atherosclerosis in the aortic root area compared with those on a 129S6 background (129-apoE). To explore atherosclerosis-responsible genetic regions, we performed a quantitative trait locus (QTL) analysis...

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Autores principales: Kayashima, Yukako, Tomita, Hirofumi, Zhilicheva, Svetlana, Kim, Shinja, Kim, Hyung-Suk, Bennett, Brian J., Maeda, Nobuyo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930552/
https://ncbi.nlm.nih.gov/pubmed/24586312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088274
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