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Aortic arch curvature and atherosclerosis have overlapping QTLs in crosses between 129S6/SvEvTac and C57BL/6J apolipoprotein E-null mice

RATIONALE: Apolipoprotein E-null mice with a 129S6/SvEvTac strain background (129-apoE) develop atherosclerotic plaques faster in the aortic arch but slower in the aortic root than those with a C57BL/6J background (B6-apoE). The shape of the aortic arch also differs in the two strains. OBJECTIVE: Si...

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Hlavní autoři: Tomita, Hirofumi, Zhilicheva, Svetlana, Kim, Shinja, Maeda, Nobuyo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848914/
https://ncbi.nlm.nih.gov/pubmed/20133902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.207175
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