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Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock()

Circadian rhythms control metabolism and energy homeostasis, but the role of the skeletal muscle clock has never been explored. We generated conditional and inducible mouse lines with muscle-specific ablation of the core clock gene Bmal1. Skeletal muscles from these mice showed impaired insulin-stim...

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Detalhes bibliográficos
Main Authors: Dyar, Kenneth A., Ciciliot, Stefano, Wright, Lauren E., Biensø, Rasmus S., Tagliazucchi, Guidantonio M., Patel, Vishal R., Forcato, Mattia, Paz, Marcia I.P., Gudiksen, Anders, Solagna, Francesca, Albiero, Mattia, Moretti, Irene, Eckel-Mahan, Kristin L., Baldi, Pierre, Sassone-Corsi, Paolo, Rizzuto, Rosario, Bicciato, Silvio, Pilegaard, Henriette, Blaauw, Bert, Schiaffino, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929910/
https://ncbi.nlm.nih.gov/pubmed/24567902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.10.005
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