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Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock()

Circadian rhythms control metabolism and energy homeostasis, but the role of the skeletal muscle clock has never been explored. We generated conditional and inducible mouse lines with muscle-specific ablation of the core clock gene Bmal1. Skeletal muscles from these mice showed impaired insulin-stim...

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Bibliografische gegevens
Hoofdauteurs: Dyar, Kenneth A., Ciciliot, Stefano, Wright, Lauren E., Biensø, Rasmus S., Tagliazucchi, Guidantonio M., Patel, Vishal R., Forcato, Mattia, Paz, Marcia I.P., Gudiksen, Anders, Solagna, Francesca, Albiero, Mattia, Moretti, Irene, Eckel-Mahan, Kristin L., Baldi, Pierre, Sassone-Corsi, Paolo, Rizzuto, Rosario, Bicciato, Silvio, Pilegaard, Henriette, Blaauw, Bert, Schiaffino, Stefano
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929910/
https://ncbi.nlm.nih.gov/pubmed/24567902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.10.005
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