Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis()

Insulin receptor substrates (Irs1, 2, 3 and Irs4) mediate the actions of insulin/IGF1 signaling. They have similar structure, but distinctly regulate development, growth, and metabolic homeostasis. Irs2 contributes to central metabolic sensing, partially by acting in leptin receptor (LepRb)-expressi...

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Main Authors: Sadagurski, Marianna, Dong, X. Charlie, Myers, Martin G., White, Morris F.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929908/
https://ncbi.nlm.nih.gov/pubmed/24567904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.10.004
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