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Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

OBJECTIVE: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH si...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Cady, Gillian, Landeryou, Taylor, Garratt, Michael, Kopchick, John J., Qi, Nathan, Garcia-Galiano, David, Elias, Carol F., Myers, Martin G., Miller, Richard A., Sandoval, Darleen A., Sadagurski, Marianna
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404104/
https://ncbi.nlm.nih.gov/pubmed/28462074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.001
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