Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

OBJECTIVE: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH si...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Cady, Gillian, Landeryou, Taylor, Garratt, Michael, Kopchick, John J., Qi, Nathan, Garcia-Galiano, David, Elias, Carol F., Myers, Martin G., Miller, Richard A., Sandoval, Darleen A., Sadagurski, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404104/
https://ncbi.nlm.nih.gov/pubmed/28462074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.001
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