Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

OBJECTIVE: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH si...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Cady, Gillian, Landeryou, Taylor, Garratt, Michael, Kopchick, John J., Qi, Nathan, Garcia-Galiano, David, Elias, Carol F., Myers, Martin G., Miller, Richard A., Sandoval, Darleen A., Sadagurski, Marianna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404104/
https://ncbi.nlm.nih.gov/pubmed/28462074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.001
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