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Complex mixtures of antibodies generated from a single production qualitatively and quantitatively evaluated by native Orbitrap mass spectrometry

Composite antibody mixtures designed to combat diseases present a new, rapidly emerging technology in the field of biopharmaceuticals. The combination of multiple antibodies can lead to increased effector response and limit the effect of escape variants that can propagate the disease. However, paral...

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Bibliografske podrobnosti
Main Authors: Thompson, Natalie J, Hendriks, Linda JA, de Kruif, John, Throsby, Mark, Heck, Albert JR
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929443/
https://ncbi.nlm.nih.gov/pubmed/24351421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27126
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