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Complex mixtures of antibodies generated from a single production qualitatively and quantitatively evaluated by native Orbitrap mass spectrometry

Composite antibody mixtures designed to combat diseases present a new, rapidly emerging technology in the field of biopharmaceuticals. The combination of multiple antibodies can lead to increased effector response and limit the effect of escape variants that can propagate the disease. However, paral...

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Bibliografiske detaljer
Main Authors: Thompson, Natalie J, Hendriks, Linda JA, de Kruif, John, Throsby, Mark, Heck, Albert JR
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929443/
https://ncbi.nlm.nih.gov/pubmed/24351421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27126
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