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Dual-tagged amyloid-β precursor protein reveals distinct transport pathways of its N- and C-terminal fragments
The amyloid-β precursor protein (APP), a type I transmembrane protein genetically associated with Alzheimer's disease, has a complex biology that includes proteolytic processing into potentially toxic fragments, extensive trafficking and multiple, yet poorly-defined functions. We recently propo...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929097/ https://ncbi.nlm.nih.gov/pubmed/24203698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt555 |
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