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Coenzyme Q10 Inhibits Glutamate Excitotoxicity and Oxidative Stress–Mediated Mitochondrial Alteration in a Mouse Model of Glaucoma
PURPOSE. To test whether a diet supplemented with coenzyme Q10 (CoQ(10)) ameliorates glutamate excitotoxicity and oxidative stress–mediated retinal ganglion cell (RGC) degeneration by preventing mitochondrial alterations in the retina of glaucomatous DBA/2J mice. METHODS. Preglaucomatous DBA/2J and...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929080/ https://ncbi.nlm.nih.gov/pubmed/24458150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12564 |
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