Brimonidine Blocks Glutamate Excitotoxicity-Induced Oxidative Stress and Preserves Mitochondrial Transcription Factor A in Ischemic Retinal Injury

Glutamate excitotoxicity-induced oxidative stress have been linked to mitochondrial dysfunction in retinal ischemia and optic neuropathies including glaucoma. Brimonindine (BMD), an alpha 2-adrenergic receptor agonist, contributes to the neuroprotection of retinal ganglion cells (RGCs) against gluta...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lee, Dongwook, Kim, Keun-Young, Noh, You Hyun, Chai, Stephen, Lindsey, James D., Ellisman, Mark H., Weinreb, Robert N., Ju, Won-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467218/
https://ncbi.nlm.nih.gov/pubmed/23056591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047098
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados