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Lefty1 and Lefty2 Control the Balance Between Self-Renewal and Pluripotent Differentiation of Mouse Embryonic Stem Cells

Lefty expression has been recognized as a stemness marker because Lefty is enriched both in undifferentiated embryonic stem cells (ESCs) and in blastocysts. Here, we examined the function of Lefty1 and Lefty2 in the maintenance of self-renewal and pluripotency of mouse ESCs (mESCs). Suppression of L...

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Autors principals: Kim, Dae-Kwan, Cha, Young, Ahn, Hee-Jin, Kim, Gwangil, Park, Kyung-Soon
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928821/
https://ncbi.nlm.nih.gov/pubmed/24147624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0220
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