Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-Synuclein: Feasibility study

Immunotherapeutic approaches reducing α-synuclein deposits may provide therapeutic benefit for Dementia with Lewy Bodies (DLB). Immunization with full-length human α-synuclein (hα-Syn) protein in a Parkinson's disease mouse model decreased the accumulation of the aggregated forms of this protei...

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Hlavní autoři: Ghochikyan, Anahit, Petrushina, Irina, Davtyan, Hayk, Hovakimyan, Armine, Saing, Tommy, Davtyan, Arpine, Cribbs, David H., Agadjanyan, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928627/
https://ncbi.nlm.nih.gov/pubmed/24361548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.12.028
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