HIV-1 evades innate immune recognition through specific co-factor recruitment

HIV-1 is able to replicate in primary human macrophages without stimulating innate immunity despite reverse transcription of genomic RNA into double stranded DNA, an activity that might be expected to trigger innate pattern recognition receptors (PRRs). We hypothesized that, if correctly orchestrate...

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Main Authors: Rasaiyaah, Jane, Tan, Choon Ping, Fletcher, Adam J., Price, Amanda J., Blondeau, Caroline, Hilditch, Laura, Jacques, David A, Selwood, David L, James, Leo C, Noursadeghi, Mahdad, Towers, Greg J
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928559/
https://ncbi.nlm.nih.gov/pubmed/24196705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12769
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