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TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1)
The TRIM family of genes is largely studied because of their roles in development, differentiation and host cell anti-viral defenses; however, roles in cancer biology are emerging. Loss of heterozygosity of the TRIM3 locus in approximately 20% of human glioblastomas raised the possibility that this...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928554/ https://ncbi.nlm.nih.gov/pubmed/23318451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.596 |
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