Nucleotide specificity in DNA scission by neocarzinostatin.

Using the DNA sequencing technique of Maxam and Gilbert, we show that the protein antibiotic neocarzinostatin, cleaves double-stranded phiX174 DNA restriction fragments almost exclusively at deoxythymidylic and deoxyadenylic acid residues in a reaction requiring 2-mercaptoethanol. Overall, deoxythym...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hatayama, T, Goldberg, I H, Takeshita, M, Grollman, A P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1978
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/151278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.8.3603
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