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Asp44 Stabilizes the Trp41 Gate of the M2 Proton Channel of Influenza A Virus
Channel gating and proton conductance of the influenza A virus M2 channel result from complex pH-dependent interactions involving the pore-lining residues His37, Trp41, and Asp44. Protons diffusing from the outside of the virus protonate His37, which opens the Trp41 gate and allows one or more proto...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3927992/ https://ncbi.nlm.nih.gov/pubmed/24139991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.029 |
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