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Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers

A series of small peptides corresponding to the amino termini of the fibrin α- and β-chains has been synthesized. The peptides glycyl-L-prolyl-L-arginyl-L-proline and glycyl-L-prolyl-L-arginylsarcosine are potent inhibitors of fibrin polymerization. Moreover, these peptides have a natural stability...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Laudano, Andrew P., Doolittle, Russell F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277910/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3085
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