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Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers

A series of small peptides corresponding to the amino termini of the fibrin α- and β-chains has been synthesized. The peptides glycyl-L-prolyl-L-arginyl-L-proline and glycyl-L-prolyl-L-arginylsarcosine are potent inhibitors of fibrin polymerization. Moreover, these peptides have a natural stability...

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Detalhes bibliográficos
Main Authors: Laudano, Andrew P., Doolittle, Russell F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392718/
https://ncbi.nlm.nih.gov/pubmed/277910
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