Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers
A series of small peptides corresponding to the amino termini of the fibrin α- and β-chains has been synthesized. The peptides glycyl-L-prolyl-L-arginyl-L-proline and glycyl-L-prolyl-L-arginylsarcosine are potent inhibitors of fibrin polymerization. Moreover, these peptides have a natural stability...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1978
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3085 |
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