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Insulin receptor: Interaction with nonreceptor glycoprotein from liver cell membranes

In crude receptor preparations (either particulate or soluble) of rat liver membranes, the insulin receptor exhibits complicated binding kinetics (two binding plateaus, half-saturated at approximately 60 pM and 700 pM insulin) and an apparent chromatographic heterogeneity, suggested by the presence...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Maturo, Joseph M., Hollenberg, Morley D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3070
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