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Insulin receptor: Interaction with nonreceptor glycoprotein from liver cell membranes

In crude receptor preparations (either particulate or soluble) of rat liver membranes, the insulin receptor exhibits complicated binding kinetics (two binding plateaus, half-saturated at approximately 60 pM and 700 pM insulin) and an apparent chromatographic heterogeneity, suggested by the presence...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Maturo, Joseph M., Hollenberg, Morley D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1978
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/277909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.7.3070
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