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Biochemical and immunochemical study of lysyl oxidase in experimental hepatic fibrosis in the rat.

Lysyl oxidase catalyzes the crosslinking of collagen and elastin. Lysyl oxidase activity was measured and localized in rat liver during the evolution of hepatic fibrosis induced by CCl4. Enzyme activity measured with DL-[6-3H]-lysine-labeled collagen substrates in liver and plasma increased sharply...

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Detalhes bibliográficos
Main Authors: Siegel, R C, Chen, K H, Greenspan, J S, Aguiar, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392683/
https://ncbi.nlm.nih.gov/pubmed/26918
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