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Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with few effective therapeutic options. Structural remodelling of the extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease p...
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| Publicado en: | Dis Model Mech |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719253/ https://ncbi.nlm.nih.gov/pubmed/29125826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030114 |
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